Portion of a free-floating collagen gel, viewed under polarized light, that has been compacted and reorganized by seeded fibroblasts. Note the strong alignment of fibers parallel to the periphery consistent with predictions of a computational mechanobiological model. Red and orange fibers are thicker; green fibers are thinner. Humphrey Laboratory
![Free-floating collagen gel](https://peb.yale.edu/sites/default/files/images/research-thrust/modeling_collagengel_940px.jpg)